SGLT2 Inhibitor


More than 34 million people in the United States currently have diabetes, and another 86 million pre-diabetics are on the cusp of developing the disease. New investigations into the safety of the heavily prescribed medication uncovered a long list of Invokana side effects.




Type 2 Diabetes

Side Effects

Ketoacidosis, bone fractures, kidney injuries, cardiac complications, UTI and yeast infections, & amputation

Illustration by Illustrator

Read more about Invokana

A photo of a diabetes patient learning about the risks of taking type 2 diabetes medications before surgery.

FDA Warns Patients to Stop Taking SGLT-2...

James Parker · April 3, 2020

The FDA released a warning about continuing the use of sodium-glucose co-transporter-2 inhibitors before surgery, informing patients that the class of diabetes medications could contribute to a higher risk of ketoacidosis.

FDA Regulation
A photo depicting a doctor talking with diabetes patient after FDA warns of rare genital gangrene linked to SGLT2 Diabetes Drugs.

FDA Warns of Rare Genital Gangrene Linke...

James Parker · September 17, 2018

People with diabetes taking Invokana and other SGLT2 inhibitors may be at risk for Fournier's gangrene, a flesh-eating bacterial infection affecting the groin and genitals. SGLT2 inhibitors that may potentially cause Fournier's gangrene include Invokana, Farxiga and Jardiance.

FDA Regulation
A photo of a young girl hugging her father, showing how to support people with diabetes.

How to Support People With Diabetes

Ashley Lombardo · November 20, 2017

Do you know someone with diabetes? Check out our tips on how to provide solid diabetes support to friends and family.

Health Features
An illustration of a finger being pricked by a glucose monitor, representing diabetes drug side effects.

What You Need to Know About Diabetes Drug Side Effects

Ashley Lombardo · November 8, 2017

MedTruth's National Diabetes Month focus is educating patients on how to handle diabetes drug side effects.

Health Features
Photo of young woman's bare feet which may be at risk because Invokana causes amputations

Why Does Invokana Cause Amputations?

Ashley Lombardo · September 8, 2017

While this diabetes drug is known to help lower blood sugar, many hopeful patients are also wondering why does Invokana cause amputations.

Health Features
judge makes decision on invokana lawsuit

Judge Consolidates Invokana Lawsuits In New Jersey

Ashley Lombardo · February 13, 2017

On Dec. 7, 2016, the U.S. Judicial Panel on Multidistrict Litigation ordered the cases be joined into a multidistrict legislation (MDL). More than 50 Invokana lawsuits related to the controversial diabetes drug have been consolidated in a U.S. District Court of New Jersey.

Legal Developments
FDA sign in front of building.

FDA Strengthens Kidney Warnings On Diabetes Drugs

Ashley Lombardo · July 24, 2016

The Food and Drug Administration (FDA) has updated warnings on four diabetes medications to minimize the risk of acute kidney injury. Used to treat type II diabetes, canagliflozin and dapagliflozin are sodium-glucose cotransporter-2 (SGLT2) inhibitors that work with the kidneys to maintain safe blood sugar levels.

FDA Regulation